Expert LC-MS/MS bioanalysts and world-class equipment

Mass spectrometry technology is a powerful analytical tool that plays a key role in drug development. Delivering accurate, robust and timely data is critical to every successful pre-clinical and clinical trial.

Agilex Biolabs conducts high performance, regulated bioanalysis by liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis of small molecules, peptides and proteins.

Our dedicated LC-MS/MS team of experts averages over 15 years of experience each. Our areas of expertise include: new chemical entities (NCEs), sugars, nucleotides, enantiomers, steroids, prodrugs, peptides, immunosuppressants, nanoparticles, neurotransmitters, oligonucleotides and polymeric mixtures.

With Sciex API 6500+ and 4000TM systems offering high throughput, high sensitivity and high-performance quantitation, the extended mass range of this instrumentation to 3000 m/z allows quantitative analysis of peptides and multiply charged small proteins. Our Sciex API QTRAP 5500 LC-MS/MS system offers even further sensitivity.

Assay development
Our LC-MS/MS team are experts at developing robust, compliant Assays to quantify novel compounds, including:

  • Pharmacokinetic (PK) assays
  • Pharmacodynamic (PD) assays
  • Biomarker assays
  • Cannabis assays

Assay validation
Our LC-MS/MS team are experts at full and partial validation and method transfer to ensure data integrity, validity and reliability.

Sample analysis
Our laboratory platforms perform high throughput and high-performance sample analysis, including:

  • Pharmacokinetic (PK) analysis
  • Pharmacodynamics (PD) biomarker analysis
  • Peptide/protein assays via hybrid immunocapture mass spectrometry
  • Toxicokinetic (TK) bioanalysis