Expert LC-MS/MS bioanalysts and world-class equipment

Mass spectrometry technology is a powerful analytical tool that plays a key role in drug development. Delivering accurate, robust, and timely data is critical to every successful pre-clinical and clinical trial.

Agilex Biolabs conducts high-performance, regulated bioanalysis by liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis of small molecules, peptides, and proteins.

Our dedicated LC-MS/MS team of experts averages over 15 years of experience each. Our areas of expertise include new chemical entities (NCEs), sugars, nucleotides, enantiomers, steroids, prodrugs, peptides, immunosuppressants, nanoparticles, neurotransmitters, oligonucleotides, and polymeric mixtures.

With Sciex API 6500+ and 4000 systems offering high throughput, high sensitivity, and high-performance quantitation, the extended mass range of this instrumentation to 3000 m/z allows quantitative analysis of peptides and multiply charged small proteins. Our Sciex API QTRAP 6500+ LC-MS/MS system offers even further sensitivity.

Assay development
Our LC-MS/MS team are experts at developing robust, compliant Assays to quantify novel compounds, including:

  • Pharmacokinetic (PK) assays
  • Pharmacodynamic (PD) assays
  • Biomarker assays
  • Cannabis assays

Assay validation
Our LC-MS/MS team are experts at full and partial validation and method transfer to ensure data integrity, validity and reliability.

Sample analysis
Our laboratory platforms perform high throughput and high-performance sample analysis, including:

  • Pharmacokinetic (PK) analysis
  • Pharmacodynamics (PD) biomarker analysis
  • Peptide/protein assays via hybrid immunocapture mass spectrometry
  • Toxicokinetic (TK) bioanalysis